The purpose of the article is to substantiate the selection and implementation of tools and means of enhancing the social responsibility of subjects of agribusiness environmental component, including on basis of prudent use of genetically modified organisms (GMOs) and development of manufacture of organic products related to food security in general. Research methods. The methodological basis of the study is the position of modern economic theory, economics of agribusiness enterprises, the concept of social responsibility, rational use of nature and sustainable development. The article uses general scientific methods of scientific knowledge – dialectical, historical, monographic (in determining the trends of agricultural production, nature management, its ecology and social responsibility for them); system-structural analysis and synthesis (when analysing and structuring environmental problems, developing a common strategy and tactics for solving them by means of social responsibility), as well as statistical-economic and socio-environmental studies (when setting quantitative indicators and indicators of environmental management and ecology in process of agrarian production, establishment of causal relationships between them and their measurement), expert assessments, sociological survey (in substantiating the prospects of solution environmental problems within the concept of social responsibility in the absence of statistical sources of calculations and forecasts). Research results. The article identifies features, problems and made an assessment of ecological efficiency and greening of agrarian production, incl. use of GMOs and their consequences. The necessity of social responsibility of agribusiness enterprises for ecological consequences of activity is substantiated. Its functions, principles, tools and mechanisms in solving environmental problems are defined. Advanced agricultural business entities are increasingly paying attention to reducing the negative impact of their activities on the environment. The value of such initiatives in the area of environmental responsibility is emphasized: reduction of energy and resource intensity of production; increasing the amount of waste used or disposed of by the enterprise; development and implementation of strategic programs of environmental activities, first of all, reclamation; implementation of international standards of environmental responsibility; environmental monitoring of technology, agricultural raw materials and food, and others. This indicates the gradual expansion of the priorities of the environmental component in the system of social responsibility of domestic enterprises of the agricultural sector of the economy. However, even at the leading domestic agricultural enterprises, its level does not reach international standards. It needs further development, especially at the level of large agricultural holdings and transnational agricultural corporations. Elements of scientific novelty. For the first time, within the concept of social responsibility, the environmental component was clarified and the means of its enhancement were determined in the form of prudent use of GMOs, organic production, introduction of environmentally oriented management. The importance of using the concept of social responsibility is emphasized. After all, it ensures conscious greening of agriculture at the level of all participants in the production process. Practical significance. The results and conclusions obtained in the article can be used in training and retraining of executives, specialists, owners of agribusiness enterprises, in their economic activities. It is advisable to introduce them into the work of regional authorities, rural communities, public organizations. Tabl.: 2. Refs.: 22